The aim of this study was to independently evaluate the diagnostic accuracy of three artificial intelligence (AI)-based computer aided detection (CAD) systems for detecting pulmonary tuberculosis (TB) on global migrants screening chest x-ray (CXR) cases when compared against both microbiological and radiological reference standards (MRS and RadRS, respectively). Retrospective clinical data and CXR images were collected from the International Organization for Migration (IOM) pre-migration health assessment TB screening global database for US-bound migrants.

The International Organization for Migration (IOM) Migration Health Assessment Programme (HAP), as part of the Migration Health Division, delivers pre-migration health activities as one of the most well-established and longest-standing services provided by the Organization. These activities are undertaken in the context of regular international migration at the request of receiving country governments and vary in scope according to the receiving country protocols and the epidemiological profile of the country of origin.

Pre-migration health activities (PMHAs) are one of IOM’s most well-established migration management services and are delivered through IOM’s Migration Health Assessment Programme (HAP). PMHAs are an array of procedures that are undertaken in the context of regular migration at the request of receiving country governments, and aim to achieve at least one of the following: 
• identification of health conditions of public health importance (communicable and non-communicable conditions) in relation to specific country legislation and International Health Regulations; 

The International Organization for Migration’s (IOM) Migration Health Assessment Programme (HAP), as part of the Migration Health Division, delivers pre-migration health activities as one of the most well-established and longest-standing services provided by the Organization. These activities are undertaken in the context of regular international migration at the request of receiving country governments and vary in scope according to the receiving country’s protocols and the epidemiological profile of the country of origin.