SARS-CoV-2 Genome Analysis of Japanese Travelers in Nile River Cruise

Sekizuka T.,
Kuramoto S.,
Nariai E.,
Taira M.,
Hachisu Y.,
Tokaji A.,
Shinohara M.,
Kishimoto T.,
Itokawa K.,
Kobayashi Y.,
Kadokura K.,
Kamiya H.,
Matsui T.,
Suzuki M.,
Kuroda M.
Document Type
Source Title
Frontiers in Microbiology
Frontiers Media S.A.


Japan has reported 26 cases of coronavirus disease 2019 (COVID-19) linked to cruise tours on the River Nile in Egypt between March 5 and 15, 2020. Here, we characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome of isolates from 10 travelers who returned from Egypt and from patients possibly associated with these travelers. We performed haplotype network analysis of SARS-CoV-2 isolates using genome-wide single-nucleotide variations. Our analysis identified two potential Egypt-related clusters from these imported cases, and these clusters were related to globally detected viruses in different countries. © Copyright © 2020 Sekizuka, Kuramoto, Nariai, Taira, Hachisu, Tokaji, Shinohara, Kishimoto, Itokawa, Kobayashi, Kadokura, Kamiya, Matsui, Suzuki and Kuroda.

Migration angle
Region/Country (by coverage)
Index Keywords

Article; clinical article; coronavirus disease 2019; Egypt; female; flu like syndrome; genome analysis; haplotype; human; Japanese (people); male; multiplex polymerase chain reaction; real time polymerase chain reaction; sequence alignment; sequence analysis; Severe acute respiratory syndrome coronavirus 2; single nucleotide polymorphism; sputum analysis; travel; virus genome; whole genome sequencing