SARS-CoV-2: exposure to high external doses as determinants of higher viral loads and of increased risk for COVID-19. A systematic review of the literature

The determinants of the risk of becoming infected by SARS-CoV-2, contracting COVID-19, and being affected by the more serious forms of the disease have been generally explored in merely qualitative terms. It seems reasonable to argue that the risk patterns for COVID-19 have to be usefully studied in quantitative terms too, whenever possible applying the same approach to the relationship 'dose of the exposure vs pathological response' commonly used for chemicals and already followed for several biological agents to SARS-CoV-2, too.

Clinical features and imaging findings in six coronavirus disease 2019 patients

Objective To summarize the clinical features and imaging findings of six coronavirus disease 2019 (COVID-19) patients, so as to provide evidences for early diagnosis and clinical intervention. Methods Six COVID-19 patients with positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were enrolled from the Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine from Jan. 1 to Feb. 22, 2020. The epidemiological history, clinical manifestations, imaging data and laboratory indicators were retrospectively analyzed.

Epidemie features of Coronavirus disease 2019 in Henan Province

Objective: To analyze the regional epidemic features of Coronavirus disease 2019 (COVID-19) in Henan Province, China. Methods: According to the data of COVID-19 patients and the resident population at the end of 2018 in Henan Province, statistical description and analysis of epidemiological characteristics of COVID-19 in Henan Province were conducted, including the time distribution, population distribution, and regional distribution. Results: The cumulative incidence of COVID-19 in Henan Province was 1.32/100 000, the cure rate was 98.03%, and the fatality rate was 1.73% by March 9, 2020.

Estimating the Number of People Infected with COVID-19 in Wuhan Based on Migration Data [基于迁徙数据估计武汉感染新型冠状病毒的人员数量]

The number of COVID-19 infected persons in Wuhan is estimated by statistically analyzing the ratio of daily confirmed cases number data of COVID-19 in 50 cities in China from January 29, 2020 to February 9, 2020 owing to Wuhan migration. The study finds that the mean and median of diagnosis rate of 15 cities in Hubei Province are lower than that of 35 cities outside Hubei Province.

Risk assessment of global COVID-19 imported cases into China

目的: 评估全球新型冠状病毒肺炎(COVID-19)疫情对我国的输入风险。 方法: 基于收集的疫情数据(各国家每日累计确诊病例数、境外输入病例累计确诊病例数)、人口学数据(各国人口密度、人口数)、旅客潜在来源群体信息(华侨华人常住人口数、在外中国留学生数、海外务工人员数、来华留学生数、航班旅客数估计)和全球健康安全指数(GHS)等信息,进行近期(2月1日-4月25日)和未来(4月26日-)风险分析及预测,构建输入风险得分。 结果: 各国境外输入病例数、累计确诊数、罹患率、华侨华人数、境外留学生数、来华留学生数、航班乘客数和GHS变量间有较强的正相关性。近期风险分析中,俄罗斯输入病例明显较高,英国、美国、法国、西班牙次之。在未来风险预测中,通过各国罹患率指数和平均每日入境乘客数估计值两项信息,评估美国、新加坡等44个国家为未来潜在高风险国家。 结论: 通过COVID-19疫情各国家输入风险评估,可以识别近期及未来的高风险区域,为加强疫情防控,为最终战胜疫情提高帮助。.Objective: To assess the risk of COVID-19 foreign imports cases to China.

The short-term impact of COVID-19 epidemic on the migration of Chinese urban population and the evaluation of Chinese urban resilience [COVID-19疫情对中国城市人口迁徙的短期影响及城市恢复力评价]

The COVID-19 epidemic in 2020 has a severe impact on China's national economic and social development. Evaluating the short-term impact of the COVID-19 epidemic and the recovery of China's economy and society, as well as revealing its spatiotemporal characteristics, can provide a strong support for the economic situation research and urban restoration of the normalized epidemic prevention and control stage.

Epidemiological characteristics and measures of prevention and control of imported COVID-19 cases in early phase in Shanghai

目的: 分析上海市新型冠状病毒肺炎(COVID-19)早期境外输入病例流行特征及防控措施,为输入性疫情的防控工作提供参考依据。 方法: 资料来源于全国传染病报告信息管理系统截至2020年3月30日上海市COVID-19境外输入病例数据及上海市各级CDC流行病学调查报告,相关防控措施信息来源于政府相关部门官网及发布平台。采用EpiData 3.1、Excel 2019和SAS 9.4软件进行数据整理与统计学分析。 结果: 截至2020年3月30日,上海市累计报告境外输入病例171例(确诊病例170例,无症状感染者1例)。其中,中国籍122例(71.3%,122/171),外籍49例(28.7%,49/171);年龄中位数为23(P(25),P(75):18,35)岁,男女性别比为1.3∶1,学生占56.6%(97/171);入境前发病者占45.6%(78/171);临床分型为轻/普通型病例占96.5%(165/171),中国籍和外籍病例的临床分型差异无统计学意义。流行曲线按确诊日期于3月24日达到峰值,随着防控措施"口岸联防联控机制闭环管理模式"落实,病例数逐渐下降。171例病例来源国主要为英国(37.3%,64例)、美国(18.6%,32例)、法国(11.0%,19例)和意大利(9.4%,16例)等24个国家及地区。

Fighting coronavirus at home: Visualizing “slammers” for the extended Spring Festival break in China

The beginning of 2020 has seen coronavirus spreading to many countries and regions. To contain the virus, China adopted, arguably, the most stringent quarantine countermeasures in the country’s history concerning restricting people flows, limiting outdoor activities, and extending the Spring Festival break.